|
|
Microcytic anemia, a survey of the prevalence of these diseases and of the prevalence of patients with limit values for these diseases
HAJDUCHOVÁ, Kateřina
This bachelor thesis is focused on anemia and the theoretical and practical analysis of microcytic anemias and their mechanisms. Anemia is the most widespread blood disorder. This disease affects nearly 30 % of the whole world. The theoretical part concerning microcytic anemias further analyzes three most typical microcytic disorders, iron deficiency anemia, anemia of chronic disease and thalasemia. Iron deficiency anemia is the most common, from these anemias and in the whole world. Anemias of chronic disease are detected in patients with a serious primary illness, in other words this anemia is a secondary illness. Thalasemia is not as widespread and it is less detected in patients. It is an genetical disorder of the structural composition of hemoglobin. The theoretical part also includes a section on iron metabolism and a chapter on haemoglobin. The practical part was prepared at the haematology laboratory of the Hořovice Hospital using the Allinity hq blood analyser from Abbott. In addition to the classical processing of samples on the analyzer, blood smears were created to assess the difference between a healthy individual and an individual with pathological erythrocyte changes. The number of analyzed samples was 271 and from that 31 % of the samples showed signs of anemia. These samples were predominantly from women, almost 65 %. The most represented type of anaemia, in terms of MCV, was normocytic anaemia. Microcytic anemias were evident in almost one-fifth of the anemic samples. There was a preponderance of hypochromic probands in the samples in which microcytic anemia was demonstrated. The blood smear values were supplemented with iron, transferrin and ferritin values from the biochemistry laboratory. Unfortunately, the number of these samples was not sufficient for further diagnostic evaluation.
|
guest ::
